However it does create abnormal second polar bodies and therefore possible aneuploid zygotes.
2.
This can be achieved by sequential biopsy, necessary if monogenic diseases are diagnosed, to be able to differentiate the first from the second polar body, or simultaneous biopsy if FISH is to be performed.
3.
Oogonium ( Oocytogenesis ) > Primary Oocyte ( Meiosis I ) > First Polar Body ( Discarded afterward ) + Secondary oocyte ( Meiosis II ) > Second Polar Body ( Discarded afterward ) + Ovum
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