adenosine deaminase वाक्य
उदाहरण वाक्य
मोबाइल
- Features that support a diagnosis of DBA include the presence of congenital abnormalities, macrocytosis, elevated fetal hemoglobin, and elevated adenosine deaminase levels in red blood cells.
- Researchers collected samples of DeSilva's blood, isolated some of her white blood cells, and used a retrovirus to insert a healthy adenosine deaminase ( ADA ) gene into them.
- The disease, which usually results in death from infection before age 1, was caused by the lack of a gene that makes an enzyme called adenosine deaminase, or ADA.
- This " editor " molecule, RNA adenosine deaminase, according to the theory, can change DNA coding as it is being read, and it is very attracted to the left-handed DNA.
- A version of adenosine deaminase can be extracted from cows, but that by itself is not a viable treatment, because the immune system, once repaired, would reject the cow enzyme.
- Anderson was the first to try genetic engineering to cure ADA, or adenosine deaminase, form of SCID . His technique changed the gene in blood cells instead of the bone marrow.
- "' Double-stranded RNA-specific adenosine deaminase "'is an enzyme that in humans is encoded by the " ADAR " gene ( which stands for " adenosine deaminase acting on RNA " ).
- "' Double-stranded RNA-specific adenosine deaminase "'is an enzyme that in humans is encoded by the " ADAR " gene ( which stands for " adenosine deaminase acting on RNA " ).
- The " add " gene encodes adenosine deaminase, and the adenine riboswitch that is upstream exposes the gene's start codon and the Shine-Dalgarno sequence when adenine is present in the binding pocket.
- Defects in purine catabolism can result in a variety of diseases including gout, which stems from an accumulation of uric acid crystals in various joints, and adenosine deaminase deficiency, which causes immunodeficiency.
- Striking about 50 children a year, this genetic defect deprives the body of its ability to produce the enzyme adenosine deaminase, a key component of the immune system, making the slightest infection deadly.
- Their rare genetic disease is called ADA-SCID _ severe combined immune deficiency ( SCID ) resulting from the failure of white blood cells to produce a critical enzyme, adenosine deaminase ( ADA ).
- In absence of adenosine deaminase ( ADA ) it accumulates in T lymphocytes and kills these cells resulting in a genetic disorder known as adenosine deaminase severe combined immunodeficiency disease ( ADA-SCID ).
- In absence of adenosine deaminase ( ADA ) it accumulates in T lymphocytes and kills these cells resulting in a genetic disorder known as adenosine deaminase severe combined immunodeficiency disease ( ADA-SCID ).
- This behavior facilitates adenosine deaminase translation, and in this way, the " add " adenosine riboswitch contributes to a metabolic negative feedback mechanism that regulates the amount of adenine present in the system.
- Gene therapy was first successfully demonstrated in late 1990 / early 1991 for adenosine deaminase deficiency, though the treatment was somatic-that is, did not affect the patient's germ line and thus was not heritable.
- The first gene therapy trials were conducted in 1990 on two patients with a genetic immune disorder called adenosine deaminase deficiency ( ADA ), also known as the " boy in the bubble " disease.
- Gene therapy trials to treat SCID due to deficiency of the Adenosine Deaminase ( ADA ) enzyme ( one form of SCID ) continue with relative success in the USA, Britain, Ireland, Italy and Japan.
- A 4-year-old girl who suffered from a disease that left her vulnerable to infection was given white blood cells altered to include a copy of the gene that makes adenosine deaminase or ADA, the enzyme she lacked.
- Anderson was the first to try genetic engineering to cure the ADA, or adenosine deaminase, form of severe combined immunodeficiency disorder, or SCID . His technique changed the gene in blood cells instead of the bone marrow.
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