agranulocytosis वाक्य
उदाहरण वाक्य
मोबाइल
- That in turn would lead to more cases of agranulocytosis and inevitably more deaths, the company said.
- Because of the risk of agranulocytosis, Clozaril is usually used to treat patients who are resistant to other drugs.
- One to 2 percent of people taking clozapine develop agranulocytosis and about 1 in 10, 000 die from the disorder.
- Granulocytopenia, agranulocytosis, and red-cell hypoplasia and aplasia, and megaloblastic anemia are rarely associated with the use of primidone.
- However, during these trials, an unacceptable number of patients dosed with metiamide developed agranulocytosis ( decreased white blood cell count ).
- Rare but serious ADRs associated with metoclopramide therapy include agranulocytosis, supraventricular tachycardia, hyperaldosteronism, neuroleptic malignant syndrome, akathisia and tardive dyskinesia.
- Unlike agranulocytosis which most commonly occurs in the first three months of therapy, this side effect may occur at any time during treatment.
- Patients in this category may be prescribed clozapine, a medication of superior effectiveness but several potentially lethal side effects including agranulocytosis and myocarditis.
- The risk of recurrence is approximately 40 50 % and lifelong treatment with antithyroid drugs carries some side effects such as agranulocytosis and liver disease.
- Symptoms and signs of agranulocytosis include infectious lesions of the throat, the gastrointestinal tract, and skin with an overall feeling of illness and fever.
- To formally diagnose agranulocytosis, other pathologies with a similar presentation must be excluded, such as aplastic anemia, paroxysmal nocturnal hemoglobinuria, myelodysplasia and leukemias.
- In 1988 the drug was withdrawn from the market in Spain due to risk of agranulocytosis; other countries where the drug was available added warnings to the label.
- These case reports suggest that the observed cases of the morning pseudoneutropenia did not proceed to become agranulocytosis which is a significant and dangerous side effect of some of antipsychotics.
- In agranulocytosis, the concentration of granulocytes ( a major class of white blood cells that includes neutrophils, basophils, and eosinophils ) drops below 500 cells / mm?of blood.
- Researchers estimated that the risk of developing agranulocytosis would nearly double under a bi-weekly system and nearly triple under a monthly monitoring system begun after the first six months on therapy.
- Ten percent of patients report skin eruptions ( such as macules and papules ), urticaria, dermatitis, fever, and arthralgia; 0.03 % of all patients develop agranulocytosis.
- The Centers for Disease Control traced outbreaks of agranulocytosis among cocaine users, in the US and Canada between March 2008 and November 2009, to the presence of levamisole in the drug supply.
- But clozapine has been less popular than its competitors because patients who take the medication must have frequent blood tests for agranulocytosis, a blood disorder that is an infrequent but potentially fatal side effect.
- Levamisole used as an adulterant in cocaine has resulted in 20 confirmed or probable cases of agranulocytosis, including 2 deaths, according to an alert from the Substance Abuse and Mental Health Services Administration.
- Although the reaction is generally idiosyncratic rather than proportional, experts recommend that patients using these drugs be told about the symptoms of agranulocytosis-related infection, such as a sore throat and a fever.
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