antisense rna वाक्य
उदाहरण वाक्य
मोबाइल
- The MYCN gene has an antisense RNA, N-cym or MYCNOS, transcribed from the opposite strand which can be translated to form a protein product.
- Pharmaceutical drug companies are exploring the use of antisense RNA to bind to undesired mRNA, preventing the ribosome from translating the mRNA into protein.
- Overexpression of AsdA increases " dnaA " mRNA level suggesting that the antisense RNA increases the stability of " dnaA " mRNA enhancing its translation.
- To form a functional protein from antisense RNA is as probable as reading a poem backwards and finding it makes perfect sense in another language.
- This allows the antisense RNA to act as a reversible switch that responds to changes in environmental conditions to modulate the expression of the isiA protein.
- Although this method has been shown to reduce PG enzymatic activity by 70 to 90 %, the PG antisense RNA did not hinder normal color development.
- Although RNAs often overlap transcription terminators to regulate transcription abundance, the information known about c4 antisense RNAs suggest that their terminator is more likely to be constitutive.
- Consensus secondary structure of the a1, b1 target of c4 antisense RNAs; these targets are also called IsrK . This figure is adapted from a previous publication.
- Other than methylation patterns affecting expression of TP53, microRNAs and antisense RNAs control the levels of the p53 protein by regulating expression of the p53 coding TP53 gene.
- Mice have homologues of these genes, but silence them in a different way, where biallelic expression occurs and then antisense RNA is used to silence one of the genes.
- In investigating the regulation of muscle protein production, they observed that neither mRNA nor antisense RNA injections had an effect on protein production, but double-stranded RNA successfully silenced the targeted gene.
- In studies using antisense RNA, downregulation of RAB7 gene expression in HeLa cells using antisense RNA induces severe cell vacuolation that resembles the phenotype seen in fibroblasts from patients with Ch�diak Higashi syndrome.
- In studies using antisense RNA, downregulation of RAB7 gene expression in HeLa cells using antisense RNA induces severe cell vacuolation that resembles the phenotype seen in fibroblasts from patients with Ch�diak Higashi syndrome.
- In molecular biology, "'ZNRD1 antisense RNA 1 "'( non-protein coding ), also known as "'ZNRD1-AS1 "'or HTEX4, is a long non-coding RNA . In humans, it is located in the MHC class I region of chromosome 6.
- "' Iron stress repressed RNA "'( IsrR ) is a cis-encoded antisense RNA which regulates the expression of the photosynthetic protein isiA . IsiA expression is activated by the Ferric uptake regulator protein ( Fur ) under iron stress conditions.
- Human lymphoma cell proliferation ( with t ( 14; 18 ) translocation ) could be inhibited by antisense RNA targeted at the start codon region of Bcl-2 mRNA . " In vitro " studies led to the identification of Genasense, which is complementary to the first 6 codons of Bcl-2 mRNA.
- It was shown that the proliferation of human lymphoma cells ( with t ( 14; 18 ) translocation ) could be inhibited by antisense RNA targeted at the start codon region of Bcl-2 mRNA . In vitro studies led to the identification of Genasense, which is complementary to the first 6 codons of Bcl-2 mRNA.
- The fact that the RNA structure is typically found in plasmids suggests that it might be involved in the regulation plasmid copy number by a " cis "-antisense mechanism in a manner similar to that of R1162-like plasmid antisense RNA . However, the " Bacillus "-plasmid RNA motif does not appear to be homologous to any such known RNA.
- The "'micF RNA "'is a non-coding RNA stress response gene found in " Escherichia coli " and related bacteria that post-transcriptionally controls expression of the outer membrane porin gene ompF . The micF gene encodes a non-translated 93 nucleotide antisense RNA that binds its target ompF mRNA and regulates ompF expression by inhibiting translation and inducing degradation of the message.
- A previously identified motif known as TraJ 5'UTR is also found upstream of " traJ " genes functions as the target of FinP antisense RNAs, so it is possible that " traJ "-II RNAs play a similar role as targets of an antisense RNA . However, some sequence features within the " traJ "-II RNA motif suggest that the biological RNA might be transcribed from the reverse-complement strand.
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