blood brain barrier वाक्य
उदाहरण वाक्य
मोबाइल
- Only about 5 10 % of levodopa crosses the blood brain barrier, while the remaining is metabolized elsewhere in the body.
- On the other hand, absence of the glial scar has been associated with impairments in the repair of the blood brain barrier.
- It is expressed primarily in the blood brain barrier and liver and is thought to be involved in protecting cells from toxins.
- Additionally, once the drug has entered the blood stream, L-DOPA utilizes the same pathways to cross the blood brain barrier as natural protein.
- While epoetin alpha is capable of crossing the blood brain barrier via active transport the amounts appearing in the CNS are very low.
- Moclobemide has good penetration across the blood brain barrier with peak plasma levels within the central nervous system occurring 2 hours after administration.
- Systemic injection of pilocarpine can compromise the blood brain barrier allowing pilocarpine to gain access to the brain which can lead to chronic epilepsy.
- The subarachnoid space is the location of the interface between the vascular tissue and the cerebrospinal fluid and is active in the blood brain barrier.
- Boockvar is the principal investigator of several clinical trials using blood brain barrier disruption to deliver high dose chemotherapy for patients with malignant brain tumors.
- As a result, the nervous system has a number of mechanisms designed to protect it from internal and external assaults, including the blood brain barrier.
- With Metrizamide the issue is that if entering the cranial cavity and high dose exposure to the blood brain barrier, side effects are more likely encountered.
- Some of the current DNMT inhibitors, however, like zebularine and procainamide, do not cross the blood brain barrier and would not prove as effective a treatment.
- Peripheral immune cells are called to the site of injury via these cytokines and may now migrate across the compromised blood brain barrier into the brain.
- Difenoxin crosses the blood brain barrier and induces some euphoria; it is often sold with or administered with atropine to reduce the potential for abuse and overdose.
- Several companies are trying to develop so-called small-molecule drugs that can be taken orally and pass through the blood brain barrier, but it has not proven easy.
- The vascular organ lacks a blood brain barrier, and so neurons in this region can respond to osmotic pressure factors that are present in the systemic circulation.
- Positron emission tomography ( PET ) studies, have demonstrated that aprepitant can cross the blood brain barrier and bind to NK 1 receptors in the human brain.
- Itopride poorly penetrates across the blood brain barrier because of its high polarity and thus itopride does not tend to cause any central nervous system adverse effects.
- Central nervous system adverse effects do not tend to occur due to poor penetration across the blood brain barrier, although a slight raising of prolactin levels may occur.
- Classified as a sensory circumventricular organ ( along with the SFO and AP ), It lacks the tight endothelial blood brain barrier, which is characteristic of the CVOs.
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