cholinesterase inhibitor वाक्य
उदाहरण वाक्य
मोबाइल
- However, because of its toxic effect as a cholinesterase inhibitor it has been banned in several countries, including the United States and the European Union.
- Professor Sahakian was one of the first researchers to suggest that attentional dysfunction in Alzheimer s disease could be ameliorated using pharmacotherapy, such as cholinesterase inhibitors.
- Bambuterol acts as a cholinesterase inhibitor, and can prolong the duration of action of suxamethonium ( succinylcholine ) and other drugs whose breakdown in the body depends on cholinesterase function.
- _Certain treatments developed since 1994, specifically a class of drugs known as cholinesterase inhibitors, have proven effective in improving memory, thought and reasoning abilities in patients with mild to moderate Alzheimer's.
- Given that the toxins alter acetylcholine transmission which causes the paralysis, some patients have been successfully treated with cholinesterase inhibitors, such as physostigmine or neostigmine, but success is variable and may be species-dependent, as well.
- The patient had no history of taking any particular medication that previously developed Pisa syndrome; such as neuroleptics, antidepressants, antiemetic, cholinesterase inhibitors, or any other similar form of the drugs known to onset symptoms of disease.
- The key areas of specialization in final dosage forms include neurology ( cholinesterase inhibitors, anxiolytics, psychostimulants, nootropics ), cardiology ( antiarrhythmics, energy metabolism enhancers ), infectology ( original nitrofurantoine derivatives and adamantine, quinuclidine and nitrofurane chemistry.
- "' Cymserine "'is a drug related to physostigmine, which acts as a reversible cholinesterase inhibitor, with moderate selectivity ( 15?) for the plasma cholinesterase enzyme butyrylcholinesterase, and relatively weaker inhibition of the better-known acetylcholinesterase enzyme.
- These trials ( the first multicenter ones for cholinesterase inhibitors ) established efficacy and ultimately led the first four of the five FDA-approved compounds for treating the symptoms of Alzheimer's : tacrine, rivastigmine, galantamine, donepezil and memantine
- This gives it a much more specific profile of effects that may be useful for treating Alzheimer's disease without producing side effects such as tremors, lacrimation, and salivation that are seen with the older nonselective cholinesterase inhibitors currently used for this application, such as donepezil.
- One of the first nAChR active compounds, besides nicotine, that was marketed as a drug was galantamine, a plant alkaloid that works as a weak cholinesterase inhibitor ( IC50 = 5�M ) as well as an allosteric sensitizer for nAChRs ( EC50 = 50 nM ).
- Physicians may find the use of cholinesterase inhibitors represents the treatment of choice for cognitive problems and donepezil ( Aricept ), rivastigmine ( Exelon ), and galantamine ( Reminyl ) may be recommended as a means to help with these problems and to slow or prevent the decline of cognitive function.
- Columnist Juan Gonzalez reports that on a data sheet from one of the city's main malathion suppliers, a company called Cheminova Agro, a note to physicians reads : " Fyfanon ULV ( malathion ) is a cholinesterase inhibitor affecting the central and peripheral nervous systems, and producing cardiac and respiratory depression ."
- Two Phase I clinical trials testing for safety of MSF in humans at the doses proposed for treating dementia have shown that it is well tolerated and relatively free of the side effects of nausea, vomiting, and diarrhea that are produced by the current cholinesterase inhibitors used for the treatment of Alzheimer's dementia.
- Flaccid paralysis resulting from cholinergic crisis can be distinguished from myasthenia gravis by the use of the drug edrophonium ( Tensilon ), which worsens the paralysis caused by cholinergic crisis, but strengthens the muscle in the case of myasthenia gravis . ( Edrophonium is an cholinesterase inhibitor hence increases the concentration of acetylcholine present ).
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