cytotoxin वाक्य
उदाहरण वाक्य
मोबाइल
- Pore-formation is the only known shared function in RTX cytotoxins, and pores are typically cation-selective allowing for an influx of Ca 2 + in target cells.
- Tumor necrosis factor ( TNF ) ( also known as TNF-alpha or cachectin ) is a cytotoxin which is derived from a form of white blood cell called monocytes.
- The diarrhetic syndromes observed in patients are thought to stem from the three toxins : hemolysin BL ( Hbl ), nonhemolytic enterotoxin ( Nhe ) and cytotoxin K ( CytK ).
- When " Climacostomum " is threatened by a predator, such as the ciliate " Dileptus margaritifer, " these cortical cysts release a defensive cytotoxin called Climacostol.
- Some microorganisms & ndash; for example, bacteria of the genus " Shigella " & ndash; secrete substances known as cytotoxins, which kill and damage intestinal tissue on contact.
- Mo finds Alvy dead of a cytotoxin and evidence that the robot is an experimental combat model capable of self-repair; Alvy's notes also indicate a defect, a weakness to humidity.
- Moreover, with the rising popularity of antibody-drug conjugate therapies, toxicity liabilities may be mitigated through targeted delivery of this potent cytotoxin, potentially enabling efficient therapies that use minimal quantities of this complex material.
- These proteins can potentially be a mix of neurotoxins ( which attack the nervous system ), hemotoxins ( which attack the circulatory system ), cytotoxins, bungarotoxins and many other toxins that affect the body in different ways.
- The resistance to chemotherapy seems to be reversible by administering chemo-resensitization drugs, such as verapamil, which acts not via MK alteration, but by inhibiting the P-glycoprotein pump that exports cytotoxins out of cells.
- After tuberculosis and leprosy, Buruli ulcer is the third most common mycobacteriosis of humans . " M . ulcerans " grows optimally on routine mycobacteriologic media at 33 �C and elaborates a necrotizing immunosuppressive cytotoxin ( mycolactone ).
- In an effort to address this complication, neurite outgrowths ( either axonal or dendritic ) in response to applied compounds have recently been proposed as a more accurate distinction between true neurotoxins and cytotoxins in an in-vitro testing environment.
- The company's prodrug technology renders the drug inactive until it encounters the programmed target, thereby delivering the cytotoxin directly to the cancer or the vessels that support it, while potentially avoiding the side effects associated with current chemotherapies.
- Venom in many snakes, such as pit vipers, affects virtually every organ system in the human body and can be a combination of many toxins, including cytotoxins, hemotoxins, neurotoxins, and myotoxins, allowing for an enormous variety of symptoms.
- After their B subunit binds to receptors on the cell surface, the toxin is enveloped by the cell and transported inside either through The mechanism pathways for the four AB5 toxins : cholera toxin, pertussis toxin, shiga toxin, and subtilase cytotoxin.
- One of the virulence factors of " C " . " difficile " that largely constitutes its resistance to antibiotics is its toxins : enterotoxin TcdA and cytotoxin TcdB . Toxins produce spores that are difficult to inactivate and remove from the environment.
- When exposed to these infected or dysfunctional somatic cells, effector CTL release perforin and granulysin : cytotoxins that form pores in the target cell's plasma membrane, allowing ions and water to flow into the infected cell, and causing it to burst or lyse.
- In children, a complication can be hemolytic uremic syndrome which then uses cytotoxins to attack the cells in the gut, so that bacteria can leak out into the blood and cause endothelial injury in locations such as the kidney by binding to globotriasylceramide ( Gb3 ).
- However, there are exceptions the venom of the black-necked spitting cobra ( " Naja nigricollis " ), an elapid, consists mainly of cytotoxins, while that of the Mojave rattlesnake ( " Crotalus scutulatus " ), a viperid, is primarily neurotoxic.
- Previous reports with purified toxins indicated that TcdA alone was enough to cause symptoms of infection and TcdB was unable to do so unless combined with TcdA . Earlier research established TcdA strictly as an enterotoxin, and TcdB as a cytotoxin, but later both toxins were found to have the same mechanism of action.
- Traitors skillfully employ advanced biotechnology to further their aims, and are known to employ fungal cytotoxins, DNA reverse transcription mutation agents ( to inject false memories and appearances in order to forestall recognition and testimony during interrogations ), as well as technology to petrify dead bodies in order to make up wall fortifications in far offworld planets.
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