deaminase वाक्य
उदाहरण वाक्य
मोबाइल
- This gene encodes a DNA-editing deaminase that is a member of the cytidine deaminase family.
- The enzymes threonine deaminase, dihydroxy acid dehydrase and transaminase are controlled by end-product regulation.
- Michael Neuberger discovered the mechanism by which antibody diversification occurs by Activation-induced ( cytidine ) deaminase.
- PBG is then converted into hydroxymethyl bilane by the enzyme porphobilinogen deaminase, also known as hydroxymethylbilane synthase.
- This disease is caused by mutation in the double stranded RNA specific adenosine deaminase ( ADAR1 ) gene.
- The encoded protein is a cytidine deaminase that has antiretroviral activity by generating lethal hypermutations in viral genomes.
- More specifically, the catalytic domain is a zinc dependent cytidine deaminase domain and is essential for cytidine deamination.
- In some bacterial species it is also involved in the degradation of arginine ( the arginine deaminase pathway ).
- Figure 1 : Structure model of the N-terminal [ catalytic deaminase domain ] of [ APOBEC3G ].
- It is a " transition state analog inhibitor of cytidine deaminase by binding to the active size as covalent hydrates.
- The structure of 40-42 kDa porphobilinogen deaminase, which is highly conserved amongst organisms, consists of three domains.
- Biochemical analysis of A4 showed the lack of cytidine deaminase activity on single stranded DNA and it binds DNA rather weak.
- Tuberculosis pleural effusions can now be diagnosed accurately by increased levels of pleural fluid adenosine deaminase, above 40 U per liter.
- A3C was found to inhibit LINE-1 elements by directly interacting with ORF1p proteins, in a deaminase-indepedent manner.
- In 2002 this work led to the publication of the first successful gene therapy treatment for adenosine deaminase deficiency ( SCID ).
- This has already been investigated in a select few proteins such as adenosine deaminase, which acts on RNA ( ADAR ).
- Victims of the SCID disorder lack the gene that produces an enzyme known as adenosine deaminase, or " ADA ."
- The MIT scientists grew crystals of a stretch of Z-DNA tightly bound to the editing enzyme, called RNA adenosine deaminase.
- In 2002 this work led to the publication of the first successful gene therapy treatment for adenosine deaminase-deficiency ( SCID ).
- Patients with myoadenylate deaminase deficiency do not retain ribose during heavy exercise, so supplementation may be required to rebuild levels of ATP.
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