humoral immunity वाक्य
उदाहरण वाक्य
मोबाइल
- Humoral immunity refers to antibody production and the accessory processes that accompany it, including : Th2 activation and cytokine production, germinal center formation and complement activation, and opsonin promotion of phagocytosis and pathogen elimination.
- Historically, the immune system was separated into two branches : humoral immunity, for which the protective function of immunization could be found in the humor ( cell-free bodily fluid or helper T cells provide protection against different pathogens.
- The immune system may respond in multiple ways to an antigen; a key feature of this response is the production of antibodies by B cells ( or B lymphocytes ) involving an arm of the immune system known as humoral immunity.
- By interacting with CD8 molecules on surfaces of cytotoxic T cells, MHC class I mediates destruction of infected or malignant host cells, the aspect of specific immunity termed cellular immunity . ( The other arm of specific immunity is humoral immunity, whose relation to MHC is more indirect .)
- He was part of the team that identified the role of humoral immunity in the pathogenesis of MS lesions, leading to the development of B-cell based therapies for MS . He has contributed to the establishment of consortia that have identified more than 50 gene variants that contribute to MS risk.
- Rejection is an adaptive immune response via cellular immunity ( mediated by killer T cells inducing apoptosis of target cells ) as well as humoral immunity ( mediated by activated B cells secreting antibody molecules ), though the action is joined by components of innate immune response ( phagocytes and soluble immune proteins ).
- By the mid-1960s, immunologists were convinced that there were indeed two separate arms of the immune system : one dealing exclusively with the production of circulating antibodies ( humoral immunity ), and another that is involved in the delayed hypersensitivity-type reactions and graft rejections ( cell-mediated immunity ).
- Particularly important was the work of Paul Ehrlich, who proposed the side-chain theory to explain the specificity of the antigen-antibody reaction; his contributions to the understanding of humoral immunity were recognized by the award of a Nobel Prize in 1908, which was jointly awarded to the founder of cellular immunology, Elie Metchnikoff.
- The polarization during primary exposure to an antigen is key in determining a number chronic diseases, such as inflammatory bowel diseases and asthma, by skewing the immune response that memory Th cells coordinate when their memory recall is triggered upon secondary exposure to similar antigens . ( B cells express MHC class II to present antigen to Th 0, but when their B cell receptors bind matching epitopes, interactions which are not mediated by MHC, these activated B cells secrete soluble immunoglobulins : antibody molecules mediating humoral immunity .)
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