inotropic वाक्य
उदाहरण वाक्य
मोबाइल
- It is a calcium sensitizer and a selective inhibitor of phosphodiesterase 3 ( PDE3 ) with positive inotropic and vasodilator effects.
- It is a structural analog of nifedipine with positive inotropic activity, and as an aromatic it is highly lipid soluble.
- By increasing the concentration of intracellular calcium or increasing the sensitivity of receptor proteins to calcium, positive inotropic agents can increase myocardial contractility.
- Because of the negative inotropic effects, the nondihydropyridine calcium channel blockers should be avoided ( or used with caution ) in individuals with cardiomyopathy.
- PKA also phosphorylates components on myofilaments allowing actin and myosin to interact more easily and thus increasing contractility and the inotropic state of the heart.
- The measurement of the true gradient is accomplished by temporarily increasing the cardiac output by the infusion of positive inotropic agents, such as dobutamine.
- The primary antihypertensive mechanism of beta blockers is unclear, but may involve reduction in cardiac output ( due to negative chronotropic and inotropic effects ).
- For example, enlarged heart muscle ( ventricular hypertrophy ) can increase inotropic state, whereas dead heart muscle ( myocardial infarction ) can decrease it.
- Onmel / Sporanox ( Itraconazole ) exhibits a negative inotropic effect on the heart and thus could spur an additive effect when used concomitantly with Isradipine.
- T 1 AM may be part of a signaling pathway to modulate cardiac function, as the compound can induce negative inotropic effects and decrease cardiac output.
- Method and Apparatus to Allow Cyclic Pacing at an Average Rate Just Above the Intrinsic Heart Rate so as to Maximize Inotropic Pacing Effects at Minimal Heart Rates
- This can be treated with inotropic agents or by intra-aortic balloon pump, but this is regarded as temporary treatment while the underlying cause is addressed.
- UAC / UVC lines can be placed at the time of birth and allow medical staff to quickly infuse fluids, inotropic drugs, and blood if required.
- The latter property ( positive chronotropic and inotropic effects ) is particularly important, because other vasodilators used in angina may be counter productive causing coronary steal phenomenon.
- If the vagus nerve on the first heart was stimulated, negative inotropic ( beat amplitude ) and chronotropic ( beat rate ) activity were seen in both hearts.
- In higher concentrations it causes endothelium-independent vasodilation and has a negative inotropic effect on cardiac output function, thus effectively lowering blood pressure and myocardial oxygen consumption.
- Management includes looking for and removing underlying cause, including medicines ( such as a Calcium Channel blocker ) and inotropic therapy to return cardiac output back to normal.
- Non-dihydropyridine calcium channel blockers such as verapamil block the slow inward calcium current in cardiac tissues, thereby having a negatively dromotropic, chronotropic and inotropic effect.
- In addition, since SERCA is more active, the next action potential will cause an increased release of calcium, resulting in increased contraction ( positive inotropic effect ).
- The mechanism of action is through inhibiting the breakdown and thereby increasing the concentration of cAMP similar to beta adrenoreceptor agonism, resulting in inotropic effects and modest diuretic effects.
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