medulloblastoma वाक्य
उदाहरण वाक्य
मोबाइल
- In one study, Golub and colleagues found gene patterns that correlated with the prognosis for medulloblastoma, a childhood brain cancer.
- Dr . Taylor s laboratory uses the tools of forward and reverse genetics to better understand the underlying biology of medulloblastoma and ependymoma.
- Other research study groups such as The Neuroblastoma and Medulloblastoma Translational Research Consortium ( NMTRC ) also conduct clinical trials to treat relapse neuroblastoma.
- The miR-17-92 Cluster has been implicated in Medulloblastoma ( MB ) which is the most common paediatric malignant brain tumour.
- Trebor had been a typical teenager until September 2000, when he was diagnosed with medulloblastoma, a fast-growing, invasive brain tumor.
- It is important to consider AT / RT when a medulloblastoma or PNET is suspected, particularly in a child under the age of one.
- Alterations in this gene have been associated with nevoid basal cell carcinoma syndrome, basal cell carcinoma, medulloblastoma, and susceptibility to congenital macrostomia.
- Characterization of the role of JPO proteins and other novel Myc partners / targets in medulloblastoma / PNET pathogenesis is the focus of ongoing work.
- A major interest in the laboratory is to determine how c-Myc, a potent oncoprotein, specifies aggressive phenotypes in cerebellar PNET / medulloblastoma.
- Now, said Khalili, evidence suggests that JC virus also plays a role in the development of the most common brain cancer in children, medulloblastoma.
- Mutations that abnormally activate Sonic hedgehog signaling predispose to cancer of the cerebellum ( medulloblastoma ) in humans with Gorlin Syndrome and in genetically engineered mouse models.
- The MicroRNA ( miR )-124 has successfully controlled cancer progression in an " in-vitro " setting for medulloblastoma and glioblastoma cells.
- The laboratory is using a number of genome-wide techniques to identify novel tumour suppressor genes and oncogenes important in the pathogenesis of medulloblastoma and ependymoma.
- The malignant ( anaplastic ) varieties of this tumor, malignant ependymoma and the ependymoblastoma, are treated similarly to medulloblastoma but the prognosis is much less favorable.
- Catenins are known to be associated with colorectal and ovarian cancer, and they have been identified in pilomatrixoma, medulloblastoma, pleomorphic adenomas, and malignant mesothelioma.
- This demonstration was obtained by overexpressing BTG2 in a mouse model of medulloblastoma, presenting activation of the Sonic Hedgehog pathway ( heterozygous for the gene Patched1 ).
- Medulloblastoma and other primitive neuroectodermal tumors ( PNETs ) are a group of highly aggressive central nervous system tumors with a tendency to spread via cerebrospinal fluid pathways.
- BRCA2 is required in the mouse for neurogenesis and suppression of medulloblastoma . BRCA2 loss profoundly affects neurogenesis, particularly during embryonic and postnatal neural development.
- SNP array karyotyping can be used to distinguish, for example, a medulloblastoma with an isochromosome 17q from a primary rhabdoid tumour with loss of 22q11.2.
- Established medulloblastoma ( a malignant brain tumor common in childhood ) specimens express CD46, and that medulloblastoma specimens removed from patients had a high level of CD46 expression.
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