microsome वाक्य
उदाहरण वाक्य
मोबाइल
- Because of the need for a multi-part protein-system, microsomes are necessary to analyze the metabolic activity of CYPs.
- In tests with liver microsomes, dealkylation seemed to be mediated by CYP3A4, but other CYP enzymes appear to be involved as well.
- Regucalcin is expressed in the neuron of brain tissues, and the decrease of brain regucalcin causes accumulation of calcium in the brain microsomes.
- These functions include the synthesis of collagen, carnitine, and neurotransmitters; the synthesis and catabolism of tyrosine; and the metabolism of microsome.
- Preparative rotors are used in biology for pelleting of fine particulate fractions, such as cellular organelles ( mitochondria, microsomes, ribosomes ) and viruses.
- These proteins are the Sec62 proteins, believed to be associated with the Sec61 and Sec63 constituents of the general protein secretory systems of yeast microsomes.
- He also discovered cytoplasmic granules full of RNA and named them " microsomes ", which were later renamed ribosomes, the protein synthesizing machineries of cell.
- To get microsomes containing a specific CYP or for high amounts of active enzyme, microsomes are prepared from Sf9 insect cells or in yeast via heterologous expression.
- To get microsomes containing a specific CYP or for high amounts of active enzyme, microsomes are prepared from Sf9 insect cells or in yeast via heterologous expression.
- It was also found that ( " S " )-styrene oxide was preferentially hydrolyzed than the " R " enantiomer in human liver microsomes.
- In human liver microsomes, cytochrome P450-mediated styrene oxidation showed the production of more " S " enantiomer relative to the " R " enantiomer.
- The "'microsomal ethanol oxidizing system "'( MEOS ) is an alternate pathway of ethanol metabolism that occurs in the microsome in the oxidation of ethanol to acetaldehyde.
- The loss of cytochrome P-450 and monooxygenase activity seen on incubation of liver microsomes with ANTU is likely the result of the covalent binding of atomic sulfur to cytochrome P-450.
- Some lots are available to study specific populations ( example : lung microsomes from smokers or non-smokers ) or divided into classifications to meet target CYP activity levels for inhibition and metabolism studies.
- Within the cell, GGT is located in microsomes and along the biliary tract plasma membrane, GGT is more commonly measured than 5-NT because GGT testing is widely available on a variety of laboratory instruments.
- In contrast to these finding from rat liver microsomes, mammalian acyl transferase from dog lungs was found to exhibit no preference between 1-lyso-2-acyl-phosphatidylcholine and 1-acyl-2-lyso-phosphatidylcholine.
- A subset of Cytochrome P450 ( CYP450 ) microsome-bound ?-hydroxylases ( see 20-Hydroxyeicosatetraenoic acid ) metabolize arachidonic acid to 20-Hydroxyeicosatetraenoic acid ( 20-HETE ) and 19-hydroxyeicosatetraenoic acid by an omega oxidation reaction.
- It is metabolized in human hepatocytes and human microsomes to form [ 2-( 2', 6'- dichloro-4'- hydroxy-phenylamino ) phenyl ] acetoxyacetic acid as the major metabolite, which is then further conjugated.
- The C-hydroxylated metabolites may be considered as the detoxication products, while the benzenediazonium ion ( BDI ) formed by microsome-catalyzed enzymatic splitting of the azo group of Sudan I, reacts with DNA " in vitro > ".
- The expression of CYP1A1 in human livers is low, less than 0, 7 % of the total hepatic CYP expression, while it contributes up to 12 to 30 % in the oxidation of Sudan I in a set of human liver microsomes.
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