neurofilament वाक्य
उदाहरण वाक्य
मोबाइल
- Neurofilament accumulation in axons has been observed in sporadic cases of ALS as well as in SOD1 patients, possibly interfering with axonal transport, leading to cell death from SOD1 toxicity.
- Dr . Jean-Pierre Julien and his colleagues at the Montreal General Hospital Research Institute in Canada found that they could reproduce ALS in mice by giving them an abnormal neurofilament gene.
- An example of the application of this technique in neuroscience is the immunolabeling of antigens like NGF-Inducible Large External glycoprotein ( NILE-GF ), choline acetyltransferase, parvalbumin, and neurofilament protein.
- With immunohistochemistry, the chief cells located in the cell balls are positive for chromogranin, synaptophysin, neuron specific enolase, serotonin, neurofilament and Neural cell adhesion molecule; they are S-100 protein negative.
- Neuron-specific enolase ( NSE ) positive, NSE negative, synaptophysin negative, neurofilament negative, TUJ1 positive, and nestin positive have been expressed in astroblastoma cell populations, showing significant promise in neuronal stem cell treatment for the tumor.
- During a clinical trial for one of the main MS drugs, a catheter was inserted into the brain's neurofilament light chain ( NF-L ) level, in CSF and serum, is a sensitive and specific marker for white matter axonal injury
- In the adult mammal neurofilament subunit proteins coassemble " in vivo ", forming a heteropolymer that contain NF-L or alpha-internexin plus NF-M or NF-H . Peripherin and vimentin may incorporate into neurofilaments along with these proteins.
- Gigaxonin is a member of the cytoskeletal kelch ( Broad-Complex, Tramtrack and Bric a brac ) repeat family . ( Kelch repeats are predicted to form a beta-propeller shape . ) Gigaxonin plays a role in neurofilament architecture and is mutated in giant axonal neuropathy.
- As development continues into neurons the neurofilament triplet proteins ( NF-L : neurofilament low molecular mass, NF-M : neurofilament medium molecular mass, and NF-H : neurofilament high molecular mass ) are expressed in increasing molecular mass order as ?-internexin expression decreases.
- As development continues into neurons the neurofilament triplet proteins ( NF-L : neurofilament low molecular mass, NF-M : neurofilament medium molecular mass, and NF-H : neurofilament high molecular mass ) are expressed in increasing molecular mass order as ?-internexin expression decreases.
- As development continues into neurons the neurofilament triplet proteins ( NF-L : neurofilament low molecular mass, NF-M : neurofilament medium molecular mass, and NF-H : neurofilament high molecular mass ) are expressed in increasing molecular mass order as ?-internexin expression decreases.
- As development continues into neurons the neurofilament triplet proteins ( NF-L : neurofilament low molecular mass, NF-M : neurofilament medium molecular mass, and NF-H : neurofilament high molecular mass ) are expressed in increasing molecular mass order as ?-internexin expression decreases.
- The disease entities which are now considered subtypes of FTLD-FUS are atypical frontotemporal lobar degeneration with ubiquitinated inclusions ( aFTLD-U ), NIFID ( otherwise known as neurofilament inclusion body disease ) and basophilic inclusion body disease ( BIBD ), which together with ALS-FUS comprise the FUS-opathies.
- Seven genes encode for the heavy ( NF-H ), medium ( NF-M ) and light neurofilament ( NF-L ) proteins, nestin and ?-internexin in nerve cells, synemin ? and desmuslin / synemin ? ( two alternative transcripts of the DMN gene ) in muscle cells, and syncoilin ( also in muscle cells ).
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