phagosome वाक्य
उदाहरण वाक्य
मोबाइल
- In a phagosome, superoxide can spontaneously form hydrogen peroxide that will undergo further reactions to generate reactive oxygen species ( ROS ).
- For this reason, as well as to avoid phagolysosomal fusion and death, " rickettsiae " must escape from the phagosome.
- Following internalization, the microbe is enclosed in a vesicular phagosome which then undergoes fusion with primary or secondary lysosomes, forming a phagolysosome.
- Upon stimulation, granulocytes and monocytes produce reactive oxygen metabolites ( superoxide anion, hydrogen peroxide, hypochlorous acid ) which destroy bacteria inside the phagosome.
- To escape from the phagosome, the bacteria secrete phospholipase D and hemolysin C . This causes disruption of the phagosomal membrane and allows the bacteria to escape.
- For example, when a macrophage ingests a pathogenic microorganism, the pathogen becomes trapped in a phagosome which then fuses with a lysosome to form a phagolysosome.
- They can internalize and kill many microbes, each phagocytic event resulting in the formation of a phagosome into which reactive oxygen species and hydrolytic enzymes are secreted.
- When the membranes of the phagosome and lysosome'collide', the lysosomal contents are discharged in an explosive manner and toxic molecules are released into the phagosome.
- When the membranes of the phagosome and lysosome'collide', the lysosomal contents are discharged in an explosive manner and toxic molecules are released into the phagosome.
- Phosphatidylinositol and Vps34-Beclin1 signalling pathways have been implicated to traffic the endocytosed phagosome to intracellular lysosomes, where fusion of the phagosome and the lysosome produces a phagolysosome.
- Phosphatidylinositol and Vps34-Beclin1 signalling pathways have been implicated to traffic the endocytosed phagosome to intracellular lysosomes, where fusion of the phagosome and the lysosome produces a phagolysosome.
- These gold nanoshells are shuttled into tumors by the use of phagocytosis, where phagocytes engulf the nanoshells through the cell membrane to form an internal phagosome, or macrophage.
- It has been found to be important in phagosome maturation and in reducing the number of intracellular mycobacteria with the help of other mitochondrial fission proteins such as DRP1 and FIs1.
- When granules fuse with a phagosome, myeloperoxidase is released into the phagolysosome, and this enzyme uses hydrogen peroxide and chlorine to create hypochlorite, a substance used in domestic bleach.
- In addition, the " B . suis " gene for nickel transport, " nikA ", is activated by metal ion deficiency and is expressed once in the phagosome.
- Once inside the macrophage, " B . suis " is able to endure the rapid acidificiation in the phagosome to pH 4.0-4.5 by expressing metabolism genes mainly for amino acid synthesis.
- For example, following phagocytosis, the ingested particle ( or phagosome ) fuses with a lysosome containing hydrolytic enzymes to form a phagolysosome; the pathogens or food particles within the phagosome are then digested by the lysosome's enzymes.
- For example, following phagocytosis, the ingested particle ( or phagosome ) fuses with a lysosome containing hydrolytic enzymes to form a phagolysosome; the pathogens or food particles within the phagosome are then digested by the lysosome's enzymes.
- This structural characteristic allows for " B . suis " to interact with lipid rafts on the surface of macrophages to be internalized, and the formed lipid-rich phagosome is able to avoid fusion with lysosomes through this endocytic pathway.
- According to another study ( done by some of the same people cited at the bottom of paragraph 1 of this section ), as the phagosome forms or soon after it forms, it fuses with the ER to form an ER-phagosome mix compartment.
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