primaquine वाक्य
उदाहरण वाक्य
मोबाइल
- He started his research with cardiac glycosides and cardiac aglycones shifting to the synthesis of primaquine and other antimalarials, at the end he did some research in new anticancer agents
- An estimated 70 % of Nicaragua s total population ( 1.9 million people ) received chloroquine and primaquine during the peak period of disease transmission ( November ).
- Treatment of " P . vivax " requires both treatment of blood stages ( with chloroquine or ACT ) as well as clearance of liver forms with primaquine.
- Other medications that are used, alone or in combination, include pentamidine, trimetrexate, dapsone, atovaquone, primaquine, pafuramidine maleate ( under investigation ), and clindamycin.
- It is an 8-aminoquinoline, of the same family as primaquine, developed by researchers at the Walter Reed Army Institute of Research in the 1970s and tested in safety trials.
- Pamaquine is no longer available anywhere, but primaquine is still used routinely worldwide as part of the treatment of " Plasmodium vivax " and " Plasmodium ovale " malaria.
- In 1956 Alving and colleagues showed that in some African Americans the antimalarial drug primaquine induces hemolytic anemia, and that those individuals have an inherited deficiency of G6PD in erythrocytes . fava beans.
- There are few significant side effects although it has been shown that primaquine may cause anorexia, nausea, vomiting, cramps, chest weakness, anaemia, some suppression of myeloid activity and abdominal pains.
- In addition, chemoprophylaxis is started before travel, during the time of potential exposure, and for 4 weeks ( chloroquine, doxycycline, or mefloquine ) or 7 days ( atovaquone / proguanil or primaquine ) after leaving the risk area.
- Given in combination with lumefantrine, it may be followed by a 14 day regimen of primaquine to prevent relapse of " P . vivax " or " P . ovale " malarial parasites and provide a complete cure.
- It is a generic drug and is available under many brand names worldwide, including Jasoprim, Malirid, Neo-Quipenyl, Pimaquin, Pmq, Primachina, Primacin, Primaquina, Primaquine, Primaquine diphosphate, Primaquine Phosphate, and Remaquin.
- It is a generic drug and is available under many brand names worldwide, including Jasoprim, Malirid, Neo-Quipenyl, Pimaquin, Pmq, Primachina, Primacin, Primaquina, Primaquine, Primaquine diphosphate, Primaquine Phosphate, and Remaquin.
- It is a generic drug and is available under many brand names worldwide, including Jasoprim, Malirid, Neo-Quipenyl, Pimaquin, Pmq, Primachina, Primacin, Primaquina, Primaquine, Primaquine diphosphate, Primaquine Phosphate, and Remaquin.
- Where an artemisinin-based combination therapy has been adopted as the first-line treatment for " P . falciparum " malaria, it may also be used for P . vivax malaria in combination with primaquine for radical cure.
- In 1980, in areas of Andhra Pradesh State in India, residual spraying was combined with a MDA . During the period of lowest malaria incidence a single dose of chloroquine plus primaquine was distributed to the whole population in eight villages.
- This is only now achieved by administration of daily primaquine for 14 days . The main advantage of tafenoquine is that it has a long half-life ( 2 3 weeks ) and therefore a single treatment may be sufficient to clear hypnozoites.
- However, the WHO has recommended that a single dose of primaquine ( 0.25 mg / kg ) is safe to give even in individuals with G6PD deficiency, for the purpose of preventing transmission of " P . falciparum " malaria.
- As of 2016, the Centers for Disease Control and Prevention recommended the use of primaquine for primary prophylaxis prior to travel to areas with a high incidence of " P . vivax ", and for terminal prophylaxis ( anti-relapse therapy ) after travel.
- Primaquine overdose can cause a dangerous reduction in various blood cell counts, and therefore should be avoided in people at risk for agranulocytosis, which include people with conditions such as rheumatoid arthritis and lupus erythematosus, and those taking concurrent medications that also decrease blood cell counts.
- Dr . Werner Kalow, a retired University of Toronto professor and a leader in pharmacogenetics research, said one of the earliest findings of racial disparities in medicine dates back to World War II, when a group of black soldiers had adverse reactions to Primaquine, a drug used to treat malaria.
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