prohormone वाक्य
उदाहरण वाक्य
मोबाइल
- Production of T 3 and its prohormone thyroxine ( T 4 ) is activated by thyroid-stimulating hormone ( TSH ), which is released from the anterior pituitary gland.
- Another prohormone convertase, proprotein convertase 2 plays a more minor role in the first step of insulin biosynthesis, but a greater role in the first step of glucagon biosynthesis.
- The physiological activity of thyroid hormone is regulated by a system of enzymes that activate, inactivate or simply discard the prohormone T 4 and in turn functionally modify T 3 and rT 3.
- Both neuropeptides and peptide hormones are synthesized by the same sets of enzymes, which include prohormone convertases and carboxypeptidases that selectively cleave the peptide precursor at specific processing sites to generate the bioactive peptides.
- Removal of the 19-amino acid N-terminal signal peptide generates the prohormone, which is hydrolysed to AVT ( derived from amino acids 20-28 ) and neurophysin VT ( derived from amino acids 32-161 ).
- As such 17?-hydroxypregenolone represents an intermediary in the ? 5 pathway that leads from pregnenolone to DHEA . 17?-Hydroxypregneolone is also converted to 17?-hydroxyprogesterone, a prohormone for glucocorticosteroids and androstenedione through the activity of 3?-hydroxysteroid dehydrogenase.
- The FNDC5 gene encodes a prohormone, a single-pass type I membrane protein ( human, 212 amino acids; mouse and rat, 209 amino acids ) that is upregulated by muscular exercise and undergoes post-translational processing to generate irisin.
- Although CDMA was sold as a " prohormone " or " prosteroid " of chlorodehydromethyltestosterone ( CDMT ), it is likely that the conversion is far from complete and that much of the activity of the drug may be attributable to its unchanged form.
- In 2001 Arnold's company introduced the prohormone 1-Androstenediol, under the marketing name 1-AD . Like andro, 1-AD is a prohormone that is easily converted by the body into 1-testosterone, and it sold well.
- In 2001 Arnold's company introduced the prohormone 1-Androstenediol, under the marketing name 1-AD . Like andro, 1-AD is a prohormone that is easily converted by the body into 1-testosterone, and it sold well.
- It activates thyroid hormone by converting the prohormone thyroxine ( T 4 ) by outer ring deiodination ( ORD ) to bioactive thyroid, and may contribute significantly to the relative increase in thyroidal T 3 production in patients with Graves'disease and thyroid adenomas.
- It is synthesized from 11?-hydroxyandrostenedione and, to a lesser extent, 11-ketoandrostenedione ( adrenosterone ) . 11-Ketoandrostenedione has notably been sold online as an androgen prohormone, usually under the name 11-oxoandrostenedione ( 11-OXO ).
- It catalyzes the inactivation of thyroid hormone by inner ring deiodination of the prohormone thyroxine ( T 4 ) and the bioactive hormone 3, 3', 5'- triiodothyronine ( RT 3 ) and 3, 3'- diiodothyronine ( T 2 ), respectively.
- On the other hand, said Dr . Robert S . Jackson, the lead author on the study, she had " astronomical amounts " of proinsulin, a precursor molecule that is converted to insulin by an enzyme called prohormone convertase 1 ( or PC1 ).
- Although CMA was sold as a " prohormone " or " prosteroid " of chloromethyltestosterone ( CMT; also known more commonly as methylclostebol ), it is likely that the conversion is far from complete and that much of the activity of the drug may be attributable to its unchanged form.
- BNP is synthesized as a 134-amino acid preprohormone ( preproBNP ), encoded by the human gene NPPB . Removal of the 25-residue N-terminal signal peptide generates the prohormone, proBNP, which is stored intracellularly as an O-linked glycoprotein; proBNP is subsequently cleaved between arginine-102 and serine-103 by a specific convertase ( probably furin or corin ) into NT-proBNP and the biologically active 32-amino acid polypeptide BNP-32, which are secreted into the blood in equimolar amounts.
- "' 7-Ketodehydroepiandrosterone "'( "'7-keto-DHEA "'), also known as "'7-oxoprasterone "', is a steroid produced by metabolism of the prohormone dehydroepiandrosterone ( DHEA ) . 7-Keto-DHEA is not directly converted to testosterone or estrogen, and has thus been investigated as a potentially more useful relative of DHEA . It is often used as the acetate ester prodrug "'7-keto-DHEA acetate " '.
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