remyelination वाक्य
उदाहरण वाक्य
मोबाइल
- GRNOPC1 is an embryonic stem cell based drug that is designed to treat specific forms of spinal cord injury through remyelination of damaged axons.
- In addition, the interaction between transplanted cells and immune cells and the effect of inflammatory immune cells on remyelination have yet to be fully characterized.
- Possible genes involved inside this pathway are TCF4 and OLIG2 which are both expressed in high amounts in areas where remyelination has failed from demyelinating diseases.
- Studies that focused on oligodendrocytes made it possible to look at different molecular targets that could allow cells to be protected from demyelination and allow remyelination.
- Julia Ruckh and fellow researchers have used parabiosis to study remyelination from adult stem cells to see if conjoining young with older mice could reverse or delay this process.
- If polydendrocytes were capable of giving rise to myelinating oligodendrocytes, one would expect complete remyelination of pathologically demyelinated lesions such as those seen in multiple sclerosis ( MS ).
- Combining immunomodulatory therapy with strategies to protect oligodendrocytes from further degeneration and enhance remyelination present a very real means to improve clinical outcomes for chronic progressive patients in the near future.
- Possible explanations for remyelination failure include depletion of polydendrocytes over time, failure to recruit polydendrocytes to the demyelinated lesion, and failure of recruited polydendrocytes to differentiate into mature oligodendrocytes.
- These markers are specific for the different processes that drive the formation of plaques : inflammation, myelin breakdown, astrogliosis, oligodendrocyte injury, neurodegeneration and axonal loss, and remyelination.
- Anti-lingo-1 ( BIIB033 ) is a monoclonal antibody specific to the lingo-1 protein and is designed to promote remyelination ( the formation of new myelin on axons ) and neuroprotection.
- One proposed mechanism involves the accumulation of myelin debris at the axon, suggesting that the inflammatory environment may be conducive to remyelination, as does the release of growth factors by inflammatory cells and activated microglia.
- There are a variety of types of these receptors, but a majority of them tend to increase, especially in the chronic stages of demyelinating diseases, suggesting that they may be involved with remyelination failure.
- Recent work on this cell has provided needed insight on the rolling processes : the process of demyelination, the spontaneous ability of the CNS to regenerate myelin, and the inevitable failure of " remyelination ".
- Repair processes, called remyelination, also play an important role in MS . Remyelination is one of the reasons why, especially in early phases of the disease, symptoms tend to decrease or disappear temporarily.
- Repair processes, called remyelination, also play an important role in MS . Remyelination is one of the reasons why, especially in early phases of the disease, symptoms tend to decrease or disappear temporarily.
- Glial cells are important in hormonal and neuroendocrine function in the central nervous system and have an active role in sleep, cognition, synaptic function and plasticity, and promote remyelination and regeneration of injured nervous tissue.
- Even if a viable source of OPCS were found, identifying and monitoring the outcome of remyelination remains difficult, though multimodal measures of conduction velocity and emerging magnetic resonance imaging techniques offer improved sensitivity versus other imaging methods.
- Recently, she has been funded by NIH-NINDS and Jacob's Cure to study the potential of subpopulations of stem cells to promote remyelination and phenotypic rescue in animal models of white matter disease, including the Canavan mouse model.
- Distinct patterns of diffusivity in MS lesions suggest that axonal loss dominates in the T1 hypointense core and that the effects of de / remyelination may be better detected in the " T2-rim ", where there is relative preservation of structural integrity.
- These scars ( sclerae ) are the known plaques or lesions usually reported in MS . A repair process, called remyelination, takes place in early phases of the disease, but the oligodendrocytes are unable to completely rebuild the cell's myelin sheath.
remyelination sentences in Hindi. What are the example sentences for remyelination? remyelination English meaning, translation, pronunciation, synonyms and example sentences are provided by Hindlish.com.