replication fork वाक्य
उदाहरण वाक्य
मोबाइल
- There is evidence to suggest that BLM plays a role in rescuing disrupted DNA replication at replication forks.
- Chromosome combing allows a genome-wide view of the firing of origins and propagation of replication fork.
- As a result, the replication forks are constrained to always meet within the termination region of the chromosome.
- Another way to view the active helicase is its ability to directly destabilize the replication fork to promote unwinding.
- Heading towards the replication fork, the nicks ) are filled with deoxyribonucleotides and sealed by the enzyme ligase.
- This asymmetry is due the formation of the replication fork and its division into nascent leading and lagging strands.
- A number of proteins are associated with the replication fork to help in the initiation and continuation of DNA synthesis.
- The DnaB helicases loaded onto the two DNA strands thus travel in opposite directions, creating two potential replication forks.
- GINS are one of the replication proteins found at the replication forks and forms a complex with Cdc45 and Mcm.
- The clustering do "'rescue of stalled replication forks "'and favors normal progress of replication forks.
- The clustering do "'rescue of stalled replication forks "'and favors normal progress of replication forks.
- Replicative polymerases form an asymmetric dimer at the replication fork by binding to sub-units of the clamp loading factor.
- At a replication fork arrested at an ICL, FAN1 nuclease action can catalyze incisions in the double-stranded region.
- When the replication fork reaches a site of DNA damage it stalls, which can lead to lethal double strand breaks.
- Unwinding of DNA at the origin and synthesis of new strands results in replication forks growing bi-directionally from the origin.
- In order for DNA replication to occur, a replication fork is created by enzymes called helicases which unwind the DNA helix.
- As with prokaryotes, two replisomes are required, one at each replication fork located at the terminus of the replication bubble.
- As replication forks spread bidirectionally from origins of replication at ( approximately ) equal speeds, then origin position can be inferred.
- The leading strand is the template strand that is being replicated in the same direction as the movement of the replication fork.
- FAN1 recruitment and its consequent activity restrain DNA replication fork progression and prevent chromosome abnormalities from occurring when DNA replication forks stall.
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