ribonucleotide वाक्य
उदाहरण वाक्य
मोबाइल
- Tyrosine Y701 functions similarly to tyrosine Y567 in the RB69 bacteriophage orthologue as the sugar steric gate that prevents ribonucleotide incorporation.
- In her current research, Stubbe continues to study the function of ribonucleotide reductases and the mechanisms of clinically useful drugs.
- 6-MP ribonucleotide inhibits purine nucleotide synthesis and metabolism by inhibiting an enzyme called Phosphoribosyl pyrophosphate amidotransferase ( PRPP Amidotransferase ).
- The Adenine Riboswitch selectively recognizes adenine, and contains a uracil ribonucleotide in position 74 of the adenine-binding aptamer domain.
- The Guanine Riboswitch selectively recognizes guanine, and contains a cytosine ribonucleotide in position 74 of the guanine-binding aptamer domain.
- It primarily inhibits the enzyme thymidylate synthase, but also has effects on DHFR, aminoimidazole carboxamide ribonucleotide formyltransferase and glycinamide ribonucleotide formyltransferase.
- It primarily inhibits the enzyme thymidylate synthase, but also has effects on DHFR, aminoimidazole carboxamide ribonucleotide formyltransferase and glycinamide ribonucleotide formyltransferase.
- Dehydration of FGAM by enzyme FGAM cyclase results in the closure of the imidazole ring, as 5-aminoimidazole ribonucleotide ( AIR ).
- The systematic name of this enzyme class is "'urate-ribonucleotide : phosphate alpha-D-ribosyltransferase " '.
- These ribonucleotide changes are likely to be harmful, as their ribose 2-hydroxyl group increases susceptibility of the adjacent phosphodiester bond to hydrolysis.
- Prior to his move, Sanger began exploring the possibility of sequencing RNA molecules and began developing methods for separating ribonucleotide fragments generated with specific nucleases.
- Enzyme AICAR transformylase assists in the final carbon transfer from N10-formyltetrahydrofolate, forming N-formylaminoimidazole-4-carboxamide ribonucleotide ( FAICAR ).
- In a female with reduced enzyme activity, an oral dose of allopurinol would be metabolized to oxypurinol ribonucleotide, which blocks the pyrimidine biosynthetic pathway.
- 3AP is a potent inhibitor of ribonucleotide reductase, the rate determining enzyme in the supply of deoxynucleotides ( DNA building blocks ) for DNA synthesis.
- Studies have found structural similarities between the active site of pyruvate formate lyase and that of Class I and Class III ribonucleotide reductase ( RNR ) enzymes.
- Continuing down the pathway, the removal of the carbon skeleton of aspartate by SAICAR lyase results in 5-aminoimidazole-4-carboxamide ribonucleotide ( AICAR ).
- Because they can represent unnatural points of entry into natural metabolic pathways, some ( such as AICA ribonucleotide ) are of interest to researchers in developing new therapies.
- In biology thiyl radicals are responsible for the formation of the deoxyribonucleic acids, building blocks for DNA . This conversion is catalysed by ribonucleotide reductase ( see figure ).
- Without the need of a primer, RNA polymerase can initiate the synthesis of a new RNA chain using the template DNA strand to guide ribonucleotide selection and polymerization chemistry.
- In ribonucleotide reductase protein R1 from " Escherichia coli " this domain is located at the N terminus, and is composed mostly of subunits of ribonucleotide reductase.
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