bradykinin वाक्य
उदाहरण वाक्य
मोबाइल
- Mutations in the C1 inhibitor gene can cause hereditary angioedema, a genetic condition resulting from reduced regulation of bradykinin by C1-INH.
- Under physiological conditions the enzyme reaches about 60 % of its maximal activity toward angiotensin I while it reaches its full activity toward bradykinin.
- Similar to KLKB1, three tissue kallikreins KLK1, KLK2 and KLK12 also participate in regulation of blood pressure via the activation of bradykinin.
- The inactivation of bradykinin and the conversion of angiotensin I to angiotensin II in the lungs was thought to be caused by the same enzyme.
- Several blood-borne substances, such as a few types of prostaglandins, leukotrienes, serotonin and bradykinin, are excreted through the lungs.
- Bradykinin is also thought to be the cause of the dry cough in some patients on angiotensin-converting enzyme ( ACE ) inhibitor drugs.
- Overactivation of bradykinin is thought to play a role in a rare disease called hereditary angioedema, formerly known as hereditary angio-neurotic edema.
- Plasma kallikrein liberates kinins ( bradykinin and kallidin ) from the kininogens, peptides responsible for the regulation of blood pressure and activation of inflammation.
- Neurturin has been shown to upregulate B1 ( bradykinin ) receptors in neurons of mice, indicating a possible influence on pain and inflammation pathways.
- Polymorphisms in ACE or aminopeptidase P ( APP ), another enzyme responsible for bradykinin degradation ( 20 % ) may also contribute to HTRs.
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