drug toxicity वाक्य
उदाहरण वाक्य
मोबाइल
- "We are adopting a significantly more conservative recommendation profile " that allows the virus to remain in the body longer in return for sparing the patient the drug toxicities, Fauci, who is co-chairman of the panel, said in an interview.
- Even though cancer patients, many with advanced or terminal disease, flock to these trials, many experts worry about the ethics of conducting studies _ particularly the earliest human trials, called Phase 1, which investigate drug toxicity _ on desperately ill patients.
- Whether used to explain a patient's response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions ( ADRs ).
- Charles Carpenter, associate director of the Brown University AIDS program, told a Royal Society of Medicine meeting in London last week : " In retrospect, we now realize the risk of drug toxicity is greatly enhanced by taking these drugs early ."
- Ingber s group extended this technology to develop a human gut-on-a-chip that undergoes peristalsis and supports growth of a living microbiome, a kidney tubule on a chip that mimics drug toxicities, as well as a bone marrow-on-a-chip that reconstitutes a full hematopoietic niche.
- Phenytoin is primarily metabolized to its inactive form by the enzyme CYP2C9 . Variations within the CYP2C9 gene that result in decreased enzymatic activity have been associated with increased phenytoin concentrations, as well as reports of drug toxicities due to these increased concentrations.
- "' Toxgnostics "'is part of Personalized medicine as it describes the guiding principles for the discovery of pharmacogenomic biomarker tests, also referred to as companion diagnostic tests, which identify if an individual patient is likely to suffer severe drug toxicity from treatment with a specific therapeutic agent.
- Folate targeting is an imaging and drug delivery method where the folate receptor ( FR ), being upregulated on malignant and inflamed cell types, is targeted to reduce drug toxicity as well as to visualize and / or to quantify the amount of disease in cancerous and inflamed tissue.
- According to Iversen et al . ( 2006 ), the increased non-prostate cancer mortality with bicalutamide monotherapy in patients has also been seen with castration ( via orchiectomy or analogue monotherapy ) and is likely a consequence of androgen deprivation in men rather than a specific drug toxicity of bicalutamide:
- The deaths in 1993 of five patients taking an experimental hepatitis drug were caused by a previously unknown type of drug toxicity, according to a federal panel that found " no evidence of negligence or carelessness " on the part of scientists or the pharmaceutical company that sponsored the drug trials.
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