haptoglobin वाक्य
उदाहरण वाक्य
मोबाइल
- It forms a complex with high-density lipoprotein 3 ( HDL3 ) particles that also contain apolipoprotein A1 ( APOA1 ) and the hemoglobin-binding, haptoglobin-related protein ( HPR ).
- Laboratory assessment is based on a positive Direct Antiglobulin Test ( DAT ), a decrease in serum haptoglobin, and an increase in blood levels of the enzyme lactate dehydrogenase and indirect bilirubin levels.
- Haptoglobin is ordered whenever a patient exhibits symptoms of anemia, such as pallor, fatigue, or shortness of breath, along with physical signs of hemolysis, such as jaundice or dark-colored urine.
- As haptoglobin is indeed an acute-phase protein, any inflammatory process ( infection, extreme stress, burns, major crush injury, allergy, etc . ) may increase the levels of plasma haptoglobin.
- As haptoglobin is indeed an acute-phase protein, any inflammatory process ( infection, extreme stress, burns, major crush injury, allergy, etc . ) may increase the levels of plasma haptoglobin.
- Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin.
- Conversely, in extravascular hemolysis the reticuloendothelial system, especially splenic monocytes, phagocytose the erythrocytes and hemoglobin is relatively not released into circulation; however, excess hemolysis can release some hemoglobin causing haptoglobin levels to be decreased.
- If there are symptoms of anemia but both the reticulocyte count and the haptoglobin level are normal, the anemia is most likely not due to hemolysis, but instead some other error in cellular production, such as aplastic anemia
- Other tumor markers for ovarian cancer include CA19-9, CA72-4, CA15-3, immunosuppressive acidic protein, haptoglobin-alpha, OVX1, mesothelin, lysophosphatidic acid, osteopontin, and fibroblast growth factor 23.
- If the reticulocyte count is increased, but the haptoglobin level is normal, this may indicate that cellular destruction is occurring in the spleen and liver, which may indicate a drug-induced hemolysis, or a red cell dysplasia.
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