holoenzyme वाक्य
उदाहरण वाक्य
मोबाइल
- As a critical component of the DNA polymerase III holoenzyme, the clamp protein binds DNA polymerase and prevents this enzyme from dissociating from the template DNA strand.
- In the majority of cells and tissues, the expression of GCLM protein is lower than GCLC and GCLM is therefore limiting in the formation of the holoenzyme complex.
- This holoenzyme is involved in the editing of cytosine-to-uracil ( C-to-U ) nucleotide bases in apolipoprotein B and neurofibromin 1 mRNAs.
- Downey CD, Crooke E, Mchenry CS . Polymerase chaperoning and multiple ATPase sites enable the E . coli DNA polymerase III holoenzyme to rapidly form initiation complexes.
- The mediator functions as a coactivator and binds to the C-terminal domain of RNA polymerase II holoenzyme, acting as a bridge between this enzyme and transcription factors.
- A concave, acidic region of the B'subunit is tilted towards the active site of the catalytic subunit in the holoenzyme ( Janssens & Goris, 2001 ).
- TFIID and human mediator coactivator ( THRAP3 ) complexes ( mediator complex, plus THRAP3 protein ) assemble cooperatively on promoter DNA, from which they become part of the RNAPII holoenzyme.
- After assembly around the DNA, the beta subunits'affinity for the gamma subunit is replaced by an affinity for the alpha and epsilon subunits, which together create the complete holoenzyme.
- The mediator functions as a coactivator and binds to the C-terminal domain ( CTD ) of RNA polymerase II holoenzyme, acting as a bridge between this enzyme and transcription factors.
- Wieczorek A, Downey CD, Dallmann HG, Mchenry CS . Only one ATP-binding DnaX subunit is required for initiation complex formation by the Escherichia coli DNA polymerase III holoenzyme.
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