inotropic वाक्य
उदाहरण वाक्य
मोबाइल
- Cassaine can be defined as a specific inhibitor of monovalent cation transport and of Na +-K + ATPase; the result being an inotropic effect on cardiac muscle.
- Because of the negative inotropic effects of flecainide, it should be used with caution in individuals with depressed ejection fraction, and may worsen congestive heart failure in these individuals.
- Noradrenaline ( a . k . a . norepinephrine ) is an inotrope and has a positive inotropic effect on heart muscle, when binding to beta-1 adrenergic receptors on this tissue.
- Inotropes stimulate cardiac muscle ( i . e . digoxin is an inotropic agent ) whereas ionotropic agents generally requires a ligand to bind causing opening / closing of a ligand receptor gated channel.
- Disopyramide s particular efficacy is due to its potent negative inotropic effects; in head-to-head comparison, it is more effective for gradient reduction than either beta-blocker or verapamil.
- It was found to depress the tonicity of coronary vessels, improve myocardial metabolism ( so that heart can sustain hypoxia better ) and also exert a positive chronotropic and inotropic effects, thereby not precipitating angina pectoris.
- Activation of ? 1 receptors induces positive inotropic, chronotropic output of the cardiac muscle, leading to increased heart rate and blood pressure, secretion of ghrelin from the stomach, and renin release from the kidneys.
- For instance,-- ATPase found in the membrane of heart cells is an important target of cardiac glycosides ( for example digoxin and ouabain ), inotropic drugs used to improve heart performance by increasing its force of contraction.
- It is indicated when parenteral therapy is necessary for inotropic support in the short-term treatment of patients with cardiac decompensation due to depressed contractility, which could be the result of either organic heart disease or cardiac surgical procedures.
- "' Pharmacological modulation of contractility "'is performed with cardioactive "'inotropic agents "'( positive or negative inotropes ) being present in the blood stream and affecting the rate of contraction of myocardial fibers.
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