partition coefficient वाक्य
उदाहरण वाक्य
मोबाइल
- In the field of hydrogeology, the octanol-water partition coefficient, or K ow, is used to predict and model the migration of dissolved hydrophobic organic compounds in soil and groundwater.
- The suitability of directional solidification in removing a specific impurity from a certain metal depends on the partition coefficient of the impurity in the metal in question, as described by the Scheil equation.
- Of special interest is the prediction of partition coefficient log " P ", which is an important measure used in identifying " druglikeness " according to Lipinski's Rule of Five.
- While one separatory funnel is useful in separating certain compound mixtures with a carefully formulated biphasic solvent system, a series of separatory funnels may be employed to separate compounds that have different partition coefficients.
- To measure the "'partition coefficient "'of ionizable solutes, the pH of the aqueous phase is adjusted such that the predominant form of the compound is un-ionized.
- An alternative equation uses the logarithm of the ratio of potency ( measured as binding energy ) and the partition coefficient to compute a lipophilic ligand efficiency index ( LE ) with a different scale.
- USEPA is currently working on incorporating tissue residue into standards for bioaccumulating chemicals, which are usually hydrophobic with a log octanol-water partition coefficient greater than 5 ( log Kow > 5 ).
- Thus, the freely dissolved interstitial water concentration of nonionic organic chemicals can be predicted using the K OC, the organic carbon-water partition coefficient, which is a constant for each chemical:
- Partition coefficients are very important in pharmacology because they determine the extent to which a substance can pass from the blood ( an aqueous solution ) through a cell wall which is like an organic solvent.
- Partition coefficients can also be defined when one of the phases is solid, for instance, when one phase is a molten metal and the second is a solid metal, or when both phases are solids.
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