VSD is an acyanotic congenital heart defect, aka a left-to-right shunt, so there are no signs of cyanosis in the early stage.
2.
In screening for congenital heart disease in pediatric patients, an NT-proBNP cut-off value of 91 pg / mL could differentiate an acyanotic heart disease ( ACNHD ) patient from a healthy patient with a specificity of 42 %.
3.
For example, for NT-proBNP, a lower cut-off value is used in distinguishing healthy babies from those with acyanotic heart disease, compared to the cut-off value used in distinguishing healthy babies from those with congenital nonspherocytic anemia.
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