Malignancy in cancers is characterized by anaplasia, invasiveness, and metastasis.
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Whether pleomorphism-anaplasia warrants a worse prognosis has not been fully assessed so far.
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Anaplasia is the most extreme disturbance in cell growth encountered in the spectrum of cellular proliferations.
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Joshi, et al . did not find any meaningful difference in clinical outcome between cases with or without anaplasia.
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However, within-stage differences were not significant, although cases without anaplasia fared better in each stage than those with.
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Expressions of pleomorphism-anaplasia have been fully acknowledged among the multifarious features of neuroblastoma in the classification by the International Neuroblastoma Pathology Committee.
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Anaplasia or dedifferentiation : loss of differentiation of cells and of their orientation to one another and blood vessels, a characteristic of anaplastic tumor tissue.
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His doctoral thesis, on facial anaplasia, was awarded a " magna cum laude " in 1909, and published the same year.
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Chatten argued that increasing anaplasia in stage IV in comparison with stage III found in her cases suggested a trend toward higher stage ( and worse prognosis ) with anaplasia.
10.
Chatten argued that increasing anaplasia in stage IV in comparison with stage III found in her cases suggested a trend toward higher stage ( and worse prognosis ) with anaplasia.