In mice, a deletion on mtDNA causes oligospermia and asthenozoospermia, resulting in infertility.
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According to the Departamento de Bioquimica y Biologica Molecular y Celular, Universidad de Zaragoza, Haplogroup T can predispose to asthenozoospermia.
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A method to increase the chance of pregnancy is ICSI . The percentage of viable spermatozoa in complete asthenozoospermia varies between 0 and 100 %.