Thus, a cell lacking TK is resistant to bromodeoxyuridine ( BrdU ) and a cell lacking HGPRT is resistant to 6-thioguanine ( 6-TG ) and 8-azaguanine.
2.
"' 8-Azaguanine "'is a purine analog with the chemical formula C 4 H 4 N 6 O . It has been widely studied for its biological activity.
3.
Vince lactam has been extensively used for the preparation of various carbocyclic nucleosides with medicinal applications in mind, including carbocyclic puromycin ( I ), carbocyclic Ara-A ( II ), carbovir ( III ) and guanine as well as azaguanine carbocyclic derivatives ( IV)
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