cardiolipin वाक्य
उदाहरण वाक्य
मोबाइल
- Cardiolipin is a unique dimeric phosphoglycerolipid predominantly present in mitochondrial membranes.
- Cardiolipin ( CL ) is a kind of diphosphatidylglycerol lipid.
- Two phosphatidylglycerols form cardiolipin, the constituent molecule of the mitochondrial inner membrane.
- This is a family of proteins that acts as a mitochondrial phosphatase in cardiolipin biosynthesis.
- In yeast mitochondria lacking cardiolipin, the number of enzymes forming respiratory supercomplexes was significantly reduced.
- Thus, this PLS3-induced redistribution of cardiolipin during apoptosis has major effects on mitochondrial function.
- Cardiolipin contains four fatty acids rather than two, and may help to make the inner membrane impermeable.
- Additionally, TIM14 helps regulate mitochondrial morphology by complexing with prohibitins to perform disphosphoglycerolipid cardiolipin ( CL ) remodeling.
- As there are four distinct alkyl chains in cardiolipin, the potential for complexity of this molecule species is enormous.
- The ATPase function of MgtA is highly cardiolipin dependent and has been shown to detect free magnesium in the ?M range
- The dissociation of subunits VIIa and III in conjunction with the removal of cardiolipin results in total loss of enzyme activity.
- Phosphatidylcholine makes up about 26.5 %, cardiolipin 25.4 %, and phosphatidylinositol 4.5 %.
- It was subsequently deduced that PLS3 is an effector for the redistribution of cardiolipin from the inner to outer mitochondrial membrane.
- It has a high affinity for phosphatidic acid and cardiolipin and can be induced by interferon gamma and tumor necrosis factor alpha.
- However, in most animal tissues, cardiolipin contains 18-carbon fatty alkyl chains with 2 unsaturated bonds on each of them.
- Thus, when PLS3 flips cardiolipin across the inner to outer membrane of the mitochondria, the oxidative phosphorylation induced is greatly disturbed.
- Cardiolipin is found mainly in mitochondrial membranes, and calcium ions play an important role in the respiratory processes mediated by the mitochondrion.
- Its genome contains no mitochondrial DNA ( mtDNA ), and no genes for cardiolipin, a lipid for energy-transducing membranes.
- ALCAT1 is upregulated by oxidative stress and diet-induced obesity, and produces a species of cardiolipin that is highly sensitive to oxidative damage.
- Two phospholipid molecules, one cardiolipin and one phosphatidylethanolamine, are also found in the SdhC and SdhD subunits ( not shown in the image ).
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