Complications are less common in patients presenting with chondroblastoma in accessible areas.
2.
Somatic mutations in the H3F3B gene are associated with chondroblastoma.
3.
Chondroblastoma is very uncommon, accounting for only 1-2 % of all bone tumors.
4.
The highly heterogeneous nature of the tumor makes classification particularly difficult especially considering the origins of chondroblastoma.
5.
Overall, the success and method of treatment is highly dependent upon the location and size of the chondroblastoma.
6.
The prevalence of metastatic chondroblastoma, however, is quite low and is believed to be less than 1 %.
7.
Chondroblastoma shows a predilection towards the male sex, with a ratio of male to female patients of 2 : 1.
8.
These findings suggest that chondroblastoma is derived from a mesenchymal cell undergoing chondrogenesis via active growth-plate signaling pathways ( see Endochondral ossification ).
9.
An aneurysmal bone cyst can arise from a pre-existing chondroblastoma, a chondromyxoid fibroma, an osteoblastoma, a giant cell tumor, or fibrous dysplasia.
10.
Other imaging techniques involve bone scans, which may be helpful in determining the anatomical boundaries, associated edema, or biological activity of the chondroblastoma, respectively.
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