| 1. | The basophilic rim is formed as chromatolysis compresses the cytoplasmic skeleton.
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| 2. | Chromatolysis is reversed when the cell is prepared for axon regeneration.
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| 3. | By the 1970s, the conserved structural features of chromatolysis were identified.
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| 4. | A second hypothesis proposes that blockage of axonal cytoskeletal proteins causes chromatolysis.
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| 5. | The nucleus of the damaged axon undergoes chromatolysis in preparation for axon regeneration.
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| 6. | It was also observed that the integrity of mitochondria is maintained during chromatolysis.
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| 7. | Again, these expanded definitions of chromatolysis are consistent with what we now term apoptosis.
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| 8. | At this time, chromatolysis was proposed to play a major role in this physiological process.
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| 9. | Chromatolysis was also thought to be responsible for necessary cell elimination in various organs during development.
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| 10. | Axotomy also induces the loss of basophilic staining in the event of central chromatolysis of the neuronal cell.
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