In 1838, Matthias Schleiden proposed that the nucleus plays a role in generating cells, thus he introduced the name " cytoblast " ( cell builder ).
2.
The idea that cells can be generated de novo, by the " cytoblast " or otherwise, contradicted work by Robert Remak ( 1852 ) and Rudolf Virchow ( 1855 ) who decisively propagated the new paradigm that cells are generated solely by cells ( " Omnis cellula e cellula " ).
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