A similar proton movement must be facilitated in deacylation.
2.
The second step ( ) is the deacylation step.
3.
Aspartoacylase is used to metabolize N-acetyl-L-aspartate by catalyzing its deacylation.
4.
Finally, sirtuins, a family of enzymes that also possess NAD +-dependent deacylation activity, were discovered to also possess mono-ADP-ribosyl transferase activity.
5.
In addition, he showed that the concept commonly described in textbooks, that the essential fatty acid docosahexaenoic acid is introduced through the acylation-deacylation cycle in retina membranes ( and in other excitable membranes ), is incorrect.
6.
Sulfacetamide is synthesized either by direct alkylation of acetamide with 4-aminobenzenesulfonyl chloride, or by reacting 4-aminobenzenesulfonamide with acetic anhydride and subsequent selective, reductive deacylation of the resultant acetamide using a system of zinc-sodium hydroxide.
7.
One activity is designated as'pre-transfer'editing and involves the hydrolysis of activated Val-AMP . The other activity is designated'post-transfer'editing and involves deacylation of mischarged Val-tRNA ( Ile ).
8.
The intermediate is then hydrolyzed in a deacylation step, regenerating the active enzyme and resulting in the release of the second product ( the electron-deficient carbonyl carbon re-forms the double bond with the oxygen and the C-terminus of the peptide is released.
9.
Echinocandin B can undergo deacylation ( removal of the lipid side chain ) by the action of a deacylase enzyme from the filamentous bacterium " Actinoplanes utahensis ", which catalyzes the cleavage of the linoleoyl side chain; in three subsequent synthetic steps, including a chemical reacylation, the antifungal drug anidulafungin is synthesized.
10.
The protein encoded by this gene functions early in the glycosylphosphatidylinositol ( GPI ) biosynthetic pathway, catalyzing the inositol deacylation of GPI . The encoded protein is required for the production of GPI that can attach to proteins, and this may be an important factor in the transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi.
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