| 1. | In cardiac muscle, desmin is present in ?B-crystallin.
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| 2. | The presence of desmin and myogenin can be detected using immunohistochemistry.
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| 3. | Desmin is a 53.5 kD protein composed of 470 amino acids.
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| 4. | Desmin is a subunit of intermediate filaments in cardiac muscle, skeletal muscle and smooth muscle tissue.
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| 5. | Activated satellite cells also begin expressing muscle-specific filament proteins such as desmin as they differentiate.
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| 6. | Desmin has been evaluated for role in assessing the depth of invasion of urothelial carcinoma in TURBT specimens.
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| 7. | Desmin is one of the earliest protein markers for muscle tissue in embryogenesis as it is detected in the somites.
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| 8. | Later, a yeast two-hybrid method was used to demonstrate that syncoilin is a binding partner of desmin.
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| 9. | LAM cells stain positively for smooth muscle actin, vimentin, desmin, and, often, estrogen and progesterone receptors.
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| 10. | Desmin protein may also bind to the DAG complex, and regions of it are known to be involved in signaling.
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