dicoumarol वाक्य
उदाहरण वाक्य
मोबाइल
- Dicoumarol is a natural chemical substance of combined plant and fungal origin.
- Identified in 1940, dicoumarol became the prototype of the 4-hydroxycoumarin anticoagulant drug class.
- They confirmed their results by synthesizing dicoumarol and proving in 1940 that it was identical to the naturally occurring agent.
- It was found to be generally superior to dicoumarol, and in 1954 was approved for medical use in humans.
- The first drug in the class to be widely commercialized was dicoumarol itself, patented in 1941 and later used as a pharmaceutical.
- Through degradation experiments they established that the anticoagulant was 3, 3'- methylenebis-( 4-hydroxycoumarin ), which they later named dicoumarol.
- Dicoumarol does affect coagulation, and was discovered in mouldy wet sweet-clover hay, as the cause of a naturally occurring bleeding disease in cattle.
- Naturally occurring coumarin is also the basis for various 4-hydroxybenzopyrone-based molecules which occur naturally dicoumarol and are made synthetically warfarin and function as anticoagulants.
- Dicoumarol was a product of the plant molecule coumarin ( not to be confused with Couma "'d "'in, a later tradename for warfarin ).
- "' Dicoumarol "'( USAN ) is a naturally occurring anticoagulant that functions as a functional vitamin K depleter ( similar to warfarin, a drug that dicoumarol inspired ).
- "' Dicoumarol "'( USAN ) is a naturally occurring anticoagulant that functions as a functional vitamin K depleter ( similar to warfarin, a drug that dicoumarol inspired ).
- Dicoumarol itself, for a short time, was employed as a medicinal anticoagulant drug, but since the mid-1950s has been replaced by its simpler derivative warfarin, and other 4-hydroxycoumarin drugs.
- Consequently, dicoumarol may be found in decaying sweet-clover, and was the cause of the so-called "'sweet-clover disease "', recognized in cattle in the 1920s.
- It is a derivative of coumarin, a bitter-tasting but sweet-smelling substance made by plants that does not itself affect coagulation, but which is ( classically ) transformed in mouldy feeds or silages by a number of species of fungi, into active dicoumarol.
- It is used in the pharmaceutical industry as a precursor reagent in the synthesis of a number of synthetic anticoagulant pharmaceuticals similar to dicoumarol, the notable ones being warfarin ( brand name Coumadin ) and some even more potent rodenticides that work by the same anticoagulant mechanism . 4-hydroxycoumarins are a type of vitamin K antagonist.
dicoumarol sentences in Hindi. What are the example sentences for dicoumarol? dicoumarol English meaning, translation, pronunciation, synonyms and example sentences are provided by Hindlish.com.