equilin वाक्य
उदाहरण वाक्य
मोबाइल
- Equilin is one of the estrogens present in the mixture of estrogens isolated from horse urine and marketed as Premarin.
- Equilin is not normally present in women, so there has been interest in the effects of equilin on the human body.
- Equilin is not normally present in women, so there has been interest in the effects of equilin on the human body.
- Estrone is the major estrogen in Premarin ( about 50 % ) and equilin is present as about 25 % of the total.
- EEs consist primarily of sodium estrone sulfate and sodium equilin sulfate, and are very similar to conjugated equine estrogen ( CEE ) preparations such as Premarin.
- The controversy stems from a decision in 1992, when the FDA specified what ingredients must be included in generic forms of estrogen-- basically sodium estrone sulfate and sodium equilin sulfate.
- After the agency specified three other compounds needed for generic estrogen replacement drugs, in addition to sodium estrone sulfate and sodium equilin sulfate, Duramed and Barr Laboratories developed new products that met the requirements.
- Herchel Smith s work on new methods for the total synthesis of steroids led to the development of commercially feasible methods for the industrial production of estrone, equilin ( an important constituent of treatments for 19-nor-testosterone, and Norgestrel ( a novel progestogen ).
- Dr . Roberta Brinton, a molecular pharmacologist at the University of Southern California in Los Angeles, reported at the Osaka meeting that one of the hormones found in Premarin, equilin, was even more effective than estrogen in stimulating nerve-cell growth and branching in the brain.
- However, EEs and CEEs differ in the sources of their contents and in the percentages of their constituents; CEEs consist of approximately 53 % sodium estrone sulfate and 25 % sodium equilin sulfate, while EEs contain approximately 80 % sodium estrone sulfate and 11 % sodium equilin sulfate.
- However, EEs and CEEs differ in the sources of their contents and in the percentages of their constituents; CEEs consist of approximately 53 % sodium estrone sulfate and 25 % sodium equilin sulfate, while EEs contain approximately 80 % sodium estrone sulfate and 11 % sodium equilin sulfate.
- The oral ingestion of 10 mg Premarin, which contains about 4.5 mg sodium estrone sulfate and 2.5 mg sodium equilin sulfate, produces maximal plasma concentrations of estrone and equilin of 1400 pg / mL and 560 pg / mL within 3 and 5 hours, respectively.
- The oral ingestion of 10 mg Premarin, which contains about 4.5 mg sodium estrone sulfate and 2.5 mg sodium equilin sulfate, produces maximal plasma concentrations of estrone and equilin of 1400 pg / mL and 560 pg / mL within 3 and 5 hours, respectively.
- Conjugated equine estrogens ( CEEs ), such as Premarin, a commonly prescribed estrogenic drug produced from the urine of pregnant mares, include the natural steroidal estrogens equilin and equilenin, as well as, especially, estrone sulfate ( which itself is inactive and becomes active upon conversion into estrone ).
- The review also determined that two estrogens estrone sulfate and equilin sulfate were primarily responsible for the activity of Premarin, and it laid the groundwork for Abbreviated New Drug Application ( ANDA ) submissions of generic versions . and 1986 the FDA announced in the Federal Register that Premarin was effective for preventing osteoporosis.
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