| 1. | There are two layers of mesoderm; intraembryonic and extraembryonic.
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| 2. | Extraembryonic endoderm ( including Yolk sac ) is derived from hypoblast cells.
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| 3. | Trophectoderm cells form extraembryonic tissues, which act in a supporting role for the embryo proper.
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| 4. | Mammalian embryos develop two cavities : the intraembryonic coelom and the extraembryonic coelom ( or chorionic cavity ).
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| 5. | It is formed by extraembryonic mesoderm and the two layers of trophoblast that surround the embryo and other membranes.
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| 6. | In humans, the formation of extraembryonic blood vessels starts at the beginning of the third week after fertilization.
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| 7. | PGCs come from the epiblast and move to the hypoblast to form the germinal crescent ( anterior extraembryonic structure ).
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| 8. | As development progresses, small lacunae begin to form within the extraembryonic mesoderm which enlarge to become the extraembryonic coelom.
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| 9. | As development progresses, small lacunae begin to form within the extraembryonic mesoderm which enlarge to become the extraembryonic coelom.
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| 10. | ECs were first thought to arise from extraembryonic tissues because blood vessels were observed in the avian and mammalian embryos.
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