Cells remaining in the follicle then develop into the corpus luteum . ( b ) In this electron micrograph of a secondary follicle, the oocyte, theca cells ( thecae folliculi ), and developing antrum are clearly visible.
2.
During the reproductive years, most estradiol in women is produced by the granulosa cells of the ovaries by the aromatization of ? 4-androstenedione ( produced in the theca folliculi cells ) to estrone, followed by conversion of estrone to estradiol by 17?-hydroxysteroid dehydrogenase.
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