As the syndrome presents frequently as a " forme fruste " ( incomplete, or unusual form ) variant, an examination of all family members must be undertaken.
2.
Abnormal corneal topography compromises of keratoconus, pellucid marginal degeneration, or forme fruste keratoconus with an I-S value of 1.4 or more is the most significant risk factor.
3.
"' Autoimmune optic neuropathy "'( AON ), sometimes called autoimmune optic neuritis, may be a forme fruste of systemic lupus erythematosus ( SLE ) associated optic neuropathy.
4.
Sigmund Freud ( 1856 1939 ) often used the term " forme fruste " in connection with incomplete or obscured cases of neuroses and psychoses and thus the literature of psychoanalysis is replete with it . ( An equivalent term in German is " minimalvariante ", but Freud used the French version .)
5.
It was in this sense of indistinctness due to wear or through long use that the great French internist Armand Trousseau ( 1801 67 ) first employed the term in connection with an obscured form of Graves'disease, which he described as a & " maladie dite fruste par l absence du goitre et de l exophthalmie " ( & disease said to be crude [ i . e ., indistinct ] for its absence of goiter and exophthalmia )
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