| 1. | Similar orientation has been discovered in other fumarase C crystal structures.
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| 2. | Fumarase deficiency is characterized by polyhydramnios and fetal brain abnormalities.
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| 3. | Inactivity of both cytosolic and mitochondrial forms of fumarase are potential causes.
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| 4. | Fumarase comes in two forms : mitochondrial and cytosolic.
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| 5. | Molecular genetic testing for fumarase deficiency is currently available.
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| 6. | Fumarase is prevalent in both fetal and adult tissues.
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| 7. | This sibling also turned out to have fumarase deficiency.
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| 8. | Despite its biological significance, the reaction mechanism of fumarase is not completely understood.
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| 9. | His thesis project revolved around the enzyme fumarase, which is not a flavoprotein.
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| 10. | Figure 2 depicts the fumarase reaction mechanism.
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