Glycocyamine is a direct precursor of creatine and is used as a supplement.
2.
However the metabolism of creatine from glycocyamine in the liver causes a depletion of methyl groups.
3.
The purpose of the experiment was to study the creation of glycocyamine, a major source of muscle power in the human body.
4.
Creatine is synthesized primarily in the liver from the methylation of glycocyamine ( guanidino acetate, synthesized in the kidney from the amino acids arginine and glycine ) by S-adenosyl methionine.
5.
The experiment involved putting Lilly on a completely protein free diet while administering measured doses of glycine and arginine solution, the two amino acids that Borsook hypothesized were involved in the creation of glycocyamine.
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