| 1. | There has been some confusion about the role DNA gyrase plays in decatenation.
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| 2. | As with CcdB the toxin target is DNA gyrase.
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| 3. | MurI s ability to inhibit gyrase binding can proceed independently of its main function.
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| 4. | It is believed that eukaryotic cells do not contain DNA gyrase or topoisomerase IV.
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| 5. | Quinolones are antibacterial agents that act at the level of DNA by inhibiting DNA Gyrase.
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| 6. | Gyrase ( a form of topoisomerase ) relaxes and undoes the supercoiling caused by helicase.
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| 7. | Gyrase is most commonly found upstream of the replication fork, where the supercoils form.
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| 8. | Both gyrase and topoisomerase IV CTDs bend DNA, but only gyrase introduces negative supercoils.
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| 9. | Both gyrase and topoisomerase IV CTDs bend DNA, but only gyrase introduces negative supercoils.
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| 10. | Glutamate racemase performs the additional function of gyrase inhibition, preventing gyrase from binding to DNA.
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