| 1. | Patients with glucose-6-phosphate dehydrogenase risk haemolysis.
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| 2. | A positive result is indicative of intravascular haemolysis.
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| 3. | It is unclear whether or not this haemolysis is due to artesunate or to the malaria itself.
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| 4. | Glibenclamide may be not recommended in those with G6PD deficiency, as it may cause acute haemolysis.
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| 5. | The Schumm test is used to differentiate intravascular haemolysis from extravascular haemolysis, as in haemolytic anaemias.
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| 6. | The Schumm test is used to differentiate intravascular haemolysis from extravascular haemolysis, as in haemolytic anaemias.
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| 7. | It may also be implicated in damage to red blood cells ( haemolysis ), the liver, cells.
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| 8. | It is also known that saponins in general can have toxic side-effects, including the induction of haemolysis.
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| 9. | Delayed haemolysis ( occurring around two weeks after treatment ) has been observed in patients treated with artesunate for severe malaria.
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| 10. | Haptoglobin levels are low in malaria because of the haemolysis that occurs with the release of the merozoites into the blood.
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