| 1. | When glucose is transported into the cell it is phosphorylated by hexokinase.
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| 2. | By blocking the enzyme hexokinase, it prevents glucose phosphorylation.
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| 3. | A hydropathy analysis of hexokinase in yeast has been created by these standards.
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| 4. | Therefore, hexokinase is most likely not an integral membrane protein in yeast.
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| 5. | The glucose is subsequently phosphorylated to glucose-6-phosphate by hexokinase.
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| 6. | This gene encodes hexokinase 2, the predominant form found in skeletal muscle.
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| 7. | Important for glycolysis to proceed, the hexokinase reaction activates glucose for subsequent steps.
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| 8. | TIGAR binds hexokinase 2 and increases its activity by an as yet unknown mechanism.
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| 9. | Hexokinases should not be confused with glucokinase, which is a specific isoform of hexokinase.
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| 10. | In hypoxic tumors, hexokinase mRNA abundance is significantly increased as well as protein levels.
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