| 1. | Hirudin ( and related substances ) are synthesised using recombinant techniques.
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| 2. | Several other direct thrombin inhibitors are derived chemically from hirudin.
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| 3. | Hirudin is the most potent natural inhibitor of thrombin.
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| 4. | Therefore, hirudin prevents or dissolves the formation of clots and complexed thrombin.
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| 5. | The active anticoagulant component of leech saliva is a small protein, hirudin.
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| 6. | Bleeding may continue for some time, due to the leech's hirudin.
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| 7. | Revasc, also known as hirudin, is genetically-engineered from the saliva of leeches.
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| 8. | The results are expected to show Hirudin is no more effective than heparin, the current standard.
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| 9. | The three studies aimed in part at comparing heparin, which was discovered in 1916, and hirudin.
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| 10. | Unlike antithrombin, hirudin binds to and inhibits only the activated thrombin, with a specific activity on fibrinogen.
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