"' Class II "'disease ( mesangial proliferative glomerulonephritis ) is noted by mesangial hypercellularity and matrix expansion.
2.
Other pathological findings may include enlarged mesenteric lymph nodes, hypercellularity of lamina propria with " foamy macrophages ", and a concurrent decreased number of lymphocytes and plasma cells, per high power field view of the biopsy.
3.
In a further report on this study Humphries found that when the experiments were repeated with a new batch of PPF no survivors were obtained, and histology of the survivors from the original experiment showed glomerular hypercellularity which he attributed to a possible toxic effect of the Pluronic polymer.