| 1. | Homozygous mutant animals displayed increased chromosomal stability in a micronucleus test.
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| 2. | The macronucleus begins as a copy of the micronucleus.
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| 3. | They are unusual among eukaryotes in that reproduction involves a micronucleus and a macronucleus.
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| 4. | The latter is generated from the micronucleus by amplification of the genome and heavy editing.
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| 5. | The micronucleus serves as the germ line nucleus, but does not express its genes.
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| 6. | Only the DNA in the micronucleus is passed on during sexual reproduction ( conjugation ).
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| 7. | The diploid germline micronucleus is transcriptionally silent and only plays a role during sexual life stages.
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| 8. | Ciliates contain two types of nuclei : somatic " macronucleus " and the germline " micronucleus ".
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| 9. | Defects in DNA damage response can cause increased frequency of micronucleus formation and hence the occurrence of chromothripsis.
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| 10. | The cell then divides transversally, and each new cell obtains a copy of the micronucleus and the macronucleus.
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