| 1. | CO 2 lasers have been used to remove dermal neurofibromas.
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| 2. | Other similar diagnoses include molluscum contagiosum, hemangioma and neurofibroma.
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| 3. | Benign peripheral nerve sheath tumors include schwannomas and neurofibromas.
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| 4. | It is being studied to treat plexiform neurofibromas.
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| 5. | However, despite increased numbers of nonmyelinating Schwann cells, there is no neurofibroma yet.
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| 6. | Removal of plexiform neurofibromas is difficult because they can be large and cross tissue boundaries.
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| 7. | Sorafenib is being studied for treatment of unresectable plexiform neurofibroma and low-grade astrocytomas.
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| 8. | They are distinct from schwannoma and neurofibroma.
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| 9. | Plexiform neurofibromas have the potential to cause severe clinical complications if they occur in certain areas.
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| 10. | In-vitro it reduces collagen synthesis in fibroblasts, and inhibits growth of neurofibroma cells.
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