Negative feedback of progesterone inhibits hypothalamic pulsatile GnRH neurosecretion, ovulatory GnRH release and pituitary gonadotropin surges thereby effectively preventing further follicular maturation.
2.
During neurosecretion / exocytosis, SNAREs play a crucial role in vesicle docking, priming, fusion, and synchronization of neurotransmitter release into the synaptic cleft.
3.
From this, the Scharrers developed the concept of neurosecretion _ secretions from nerve cells _ that gave rise in the 1930s and early 1940s to neuroendocrinology as a new discipline.
4.
After completing his M . D . degree in 1943, Palay spent a year as an intern at New Haven Hospital, while in the evenings continuing his research into neurosecretion at the Department of Anatomy at Yale University.
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